For Medical Professionals

Various Medical Conditions and effect of hyperbaric oxygen therapy on them :-

No. Condition Effect of therapy
1 Diabetic Wound Improves collagen & fibroblasts synthesis (new tissue formation) and angiogenesis (new blood vessel formation).
2 Problem Wounds Improves collagen & fibroblasts network angiogenesis promotes healing.
3 Craniocerebral/Traumatic Brain Injury Reduces edema in brain, repairing the metabolic injury in the brain cells. Also prevents inflammation in the case of severe brain injuries in just a few sessions during the first 72 hours post damage.
4 Compromised Skin Grafts and Flaps Improves fibroblast and collagen synthesis (new tissue formation) and angiogenesis (new blood vessel formation) which is highly likely to benefit a compromised graft or flap.
5 Crush Injury and Compartment Syndrome Reduces blood flow that allows capillaries to resabsorb extra fluid, resulting in decreased edema. As a gradient of oxygenation is based on blood flow, the oxygen tissue tensions can be returned to normal, allowing the host defenses to function properly.
6 Necrotizing Soft Tissue Infections Controls the infection and reduces tissue loss. Firstly, HBOT is toxic to anaerobic bacteria. Next, HBOT improves polymorphonuclear function and bacterial clearance. May decrease neutrophil adherence based on the inhibition of beta-2 integrin function. In the event of clostridial myonecrosis, HBOT can also stop the production of the alpha toxin.
7 Refractory Osteomyelitis Provides periodic elevation of bone and tissue oxygen tension from hypoxic to normal or hyperoxic levels. This promotes angiogenesis, increased leukocyte killing, aminoglycoside transport across bacterial cell walls and osteoclast activity in removing necrotic bone-tissue.
8 Thermal Burns Decreases fluids, decreases full thickness injury, decreases edema, decreases inflammation, increases leukocyte count.
9 Intracranial Abscess Induces high oxygen tension in bone and blood tissue, which helps to prevent anaerobic bacterial growth, including organisms commonly found in ICA. Also helps to reduce increased intracranial pressure (ICP).
10 Exceptional Blood Loss Supplies enough oxygen to support the basic metabolic needs in cases where patient has lost sufficient red-cell mass to compromise the fundamental respiratory requirements.
11 Radiation Tissue Damage Increases angiogenesis, stimulates immune response, promotes healing, decreases morbidity.
12 Post Anoxic Encephalopathy Increases oxygen supply to ischemic neurons, reduces edemas and revers reduced flexibility of erythrocytes.
13 Cerebral Palsy / Autism Causes significant improvement in motor functions, speech, attention, memory and functional skills.
14 Ischaemic Stroke Stimulates the growth of new blood vessels and repairs the damaged ones, aiding the stroke patient in reducing spasticity and swellings. Also improves their general neurological condition.
Besides the aforementioned conditions, HBOT is also very useful in easing decompression sickness, treating carbon monoxide or cyanide poisoning, rectifying air embolisms and abating acute migraines for examples.